Population of St. Joseph Missouri over the years:
| Year | Population |
| 1843 | 200 |
| 1845 | 600 |
| 1850 | 3,460 |
| 1860 | 8,932 |
| 1870 | 19,565 |
| 1880 | 32,431 |
| 1890 | 52,324 |
| 1900 | 102,979 |
| 1910 | 77,403 |
| 1920 | 77,939 |
| 1930 | 80,935 |
| 1940 | 75,711 |
| 1950 | 78,588 |
| 1960 | 79,673 |
| 1970 | 72,748 |
| 1980 | 76,691 |
| 1990 | 71,852 |
| 2000 | 73,990 |
| 2010 | 76,780 |
| 2020 | 72,293 |
| 2021 | 71,602 |
